Scale up of oscillatory
helically baffled reactors
The Oscillatory Baffled Reactor (OBR) is an
intensified design of continuous plug flow
reactor (PFR) in which plug flow behaviour can
be achieved at very low net flow rates (laminar
flow regime). OBRs consist of tubes with
periodically spaced baffles of various designs
(orifice, helical, integral, etc). There is a
net flow through the reactor, and a superimposed
oscillatory flow. Resultantly, the OBR’s niche
application is to operate “long” reactions in
continuous mode. This is usually impractical in
conventional tubular reactors.
Scale-up of conventional reactors, e.g. stirred
tank reactors, is unpredictable due to the
non-uniform mixing at large scale, leading to
variations in the concentrations and
temperatures. This means that optimum conditions
obtained from laboratory scales cannot be
directly used at large scales without
re-optimisation. Therefore, process development
time and product-to-market times would increase.
However, scale-up of OBRs should be more
predictable, as the flow structures produced at
5 mm scales (diameter) can be reproduced at
larger scales (25–200 mm diameters).
Recent studies on oscillatory helically baffled
reactors (OHBRs) at small scales (millilitre
volumes) found that the helical baffle design
could provide high degrees of plug flow across a
broad operating window due to the combined
effect of vortex formation and swirling. In this
study, the scale-up characteristics of helically
baffled OBRs are being explored using the
residence time distribution (RTD).
It has been found that the behaviour of RTD is
the same at all tested scales (10–25 mm
diameters, with respective reactor volumes of
0.078 L and 0.834 L) when the geometric and
dynamic parameters are maintained. The degree of
plug flow was quantified in terms of the number
of equivalent tanks-in-series (N). At a fixed
geometry, a scale-up correlation was established
and validated over a range of operating
conditions such as oscillatory conditions (Strouhal
number,
St,
and oscillatory Reynolds number,
Reo)
and the velocity ratio of oscillatory to net
flow (ψ).
This correlation has also been successfully
extrapolated and validated at 50 mm diameters.
Current work is focussed on
achieving scale-up through mass transfer (using
multi-orifice baffles) and heat transfer (using
regular orifice baffles), as these will have
implications on other types of process (e.g.
biological processes).
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